Caprine Arthritis Encephalitis Complex, by G. Bertoni; A0902.0707
نویسنده
چکیده
Introduction The CAEV virus Taxonomy Virus genome and replication Target cells in vivo and in vitro Clinical and pathological aspects Arthritis: Clinical aspects Arthritis: Pathological and histopathological changes Mastitis Encephalitis Pneumonia Immunopathological aspects of CAEV induced disease Restriction of virus replication in vivo Immunopathology and B cell immune response Immunopathology and T cell immune response Diagnosis of SRLV infections Serological methods PCR diagnostic procedure Diagnostic implications of genomic and antigenic variability Control of SRLV infections Vaccination against SRLV
منابع مشابه
Vaccination with a T-cell-priming Gag peptide of caprine arthritis encephalitis virus enhances virus replication transiently in vivo.
CD4+ T cells are involved in several immune response pathways used to control viral infections. In this study, a group of genetically defined goats was immunized with a synthetic peptide known to encompass an immunodominant helper T-cell epitope of caprine arthritis encephalitis virus (CAEV). Fifty-five days after challenge with the molecularly cloned CAEV strain CO, the vaccinated animals had ...
متن کاملDemonstration of coinfection with and recombination by caprine arthritis-encephalitis virus and maedi-visna virus in naturally infected goats.
Recombination of different strains and subtypes is a hallmark of lentivirus infections, particularly for human immunodeficiency virus, and contributes significantly to viral diversity and evolution both within individual hosts and within populations. Recombinant viruses are generated in individuals coinfected or superinfected with more than one lentiviral strain or subtype. This, however, has n...
متن کاملAchievements of an eradication programme against caprine arthritis encephalitis virus in South Tyrol, Italy
Small ruminant lentivirus infections in goats affect both production and animal welfare. This represents a threat to the qualitative and quantitative growth of goat farming, recently observed in mountainous regions such as the Autonomous Province of Bolzano - South Tyrol (Italy). To monitor and eradicate the caprine arthritis encephalitis virus in this goat population, a compulsory eradication ...
متن کاملPriming with tat-deleted caprine arthritis encephalitis virus (CAEV) proviral DNA or live virus protects goats from challenge with pathogenic CAEV.
We previously reported that infection of goats with caprine arthritis encephalitis virus (CAEV) tat- proviral DNA or virus results in persistent infection, since the animals seroconverted and direct virus isolation from cultures of blood-derived macrophages was positive. In this study we wanted to determine whether goats injected with CAEV tat- proviral DNA or virus were protected against chall...
متن کاملNeutralizing antibody response of rabbits and goats to caprine arthritis-encephalitis virus.
Rabbits were immunized with purified caprine arthritis-encephalitis virus and examined for neutralizing activity. Analysis of virus-antiserum interaction at 37 degrees C demonstrated little loss of viral infectivity after incubation with heat-inactivated rabbit antiserum for 60 min. However, sensitization of virus (as assessed by the addition of complement) occurred almost immediately and was 9...
متن کامل